It's 1999 and over the course of one 12 hour shift at an Arkansas hospital, a junkie nurse (Angela Bettis), her scheming cousin (Chloe Farnworth) and a group of black market organ-trading criminals (Mick Foley, David Arquette, Dusty Warren) start a heist that could lead to their imminent demises.

The Peanut Butter Falcon is an adventure story set in the world of a modern Mark Twain that begins when Zak (22), a young man with Down syndrome, runs away from the nursing home where he lives to chase his dream of becoming a professional wrestler by attending the wrestling school The Salt Water Redneck. Through circumstances beyond their control Tyler (32), a small-time outlaw on the run, becomes Zak's unlikely coach and ally. Together they wind through deltas, elude capture, drink whisky, find...